[Myelofibrosis in a benzene-exposed cleaning worker]
Roser Bausà1, Lydia Navarro, Imma Cortès-Franch
1Servicio de Prevención de Riesgos Laborales del Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. rbausa@santpau.cat.
Abstract:
Long-term exposure to benzene has been associated with several blood malignancies, including aplastic anemia, myeloproliferative neoplasms, and different leukemias. We present a case of primary myelofibrosis in a 59-year-old woman who worked as a cleaner at a car dealership and automobile mechanic shop. For 25 years, she used gasoline as a degreaser and solvent to clean engine parts, floors and work desks on a daily basis. She was referred by her primary care provider to the Occupational Health Unit of Barcelona to assess whether her illness was work-related. Review of her job history and working conditions revealed chronic exposure to benzene in the absence of adequate preventive measures. An association between benzene exposure and myeloproliferative disease was established, suspicious for an occupational disease.
Related Concept Videos
NMR Spectroscopy of Benzene Derivatives
Electrophilic Aromatic Substitution: Sulfonation of Benzene
Electrophilic Aromatic Substitution: Chlorination and Bromination of Benzene


