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Updated: Feb 26, 2026

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors
Published on: February 16, 2024
Gangliocytic paraganglioma: an unusual cause of upper gastrointestinal bleeding
Yolanda Sánchez Torrijos1, Rafael León Montañés2, María Ángeles Mejías Manzano3
1Hospital Universitario Virgen del Rocío, España.
Abstract:
Gangliocytic paraganglioma is an uncommon tumor, which is usually located in the ampulla of Vater, and may get confused in the differential diagnosis with ampuloma or GIST. Here we present a case of a patient with upper gastrointestinal bleeding as a predominant symptom, objectified by endoscopy an ulcerative polypoid mass at the juxtapilar level, with histological result of gangliocítica paraganglioma after multiple biopsies, and finally surgical resection. The interest of this case is the difficulty for diagnosing, the different treatments and prognosis that this implies, especially for the tumor location, as surgery can lead to great complications.
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