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Isolation of Leukocytes from Human Breast Milk for Use in an Antibody-dependent Cellular Phagocytosis Assay of HIV Targets
Published on: September 6, 2019
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Cells of human breast milk
Malgorzata Witkowska-Zimny1, Ewa Kaminska-El-Hassan1
1Department of Biophysics and Human Physiology, Medical University of Warsaw, Chalubinskiego 5, 02-004 Warsaw, Poland.
Cellular & Molecular Biology Letters
|July 19, 2017
Summary
Human milk contains diverse cells, including progenitor/stem cells, and a microbiome. This review explores their roles in infant health and gut colonization.
Area of Science:
- Human biology
- Microbiology
- Cell biology
Background:
- Human milk is a complex biological fluid essential for infant nutrition.
- Breast milk harbors a diverse microbiome and various cell types with incompletely understood functions.
- Cellular components like progenitor/stem cells are notable constituents of human milk.
Purpose of the Study:
- To review the current knowledge on breast milk cellular components.
- To discuss the potential roles of these cells in infant health and gastrointestinal tract colonization.
- To highlight stem cells and probiotic bacteria within breast milk.
Main Methods:
- Literature review of scientific studies on breast milk composition.
- Analysis of research on cellular elements in human milk.
- Synthesis of findings regarding leukocytes, epithelial cells, stem cells, and bacteria.
Main Results:
- Human milk contains leukocytes, epithelial cells, and progenitor/stem cells.
- A diverse microbiome, including potentially probiotic bacteria, is present in breast milk.
- The physiological roles and health implications of these cellular components are under investigation.
Conclusions:
- Breast milk cellular components and microbiome play significant roles in infant development.
- Further research is needed to elucidate the precise functions of these cells and bacteria.
- Understanding breast milk's cellular complexity is crucial for infant health and nutrition science.
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