Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

1.8K
Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
1.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recurrence-free survival is prolonged in high-grade serous ovarian cancer with high PD-L1 expression.

BMC cancer·2026
Same author

Intraoperative endoscopic pylorus dilatation during minimally invasive <i>Ivor Lewis</i> oesophagectomy to prevent delayed gastric conduit emptying (DGCE): protocol for the WIDE randomised controlled trial.

BMJ open·2026
Same author

Effects of Gastric Bypass on Beta-cell function and Insulin sensitivity in Patients with Non-Severe Obesity (BMI<35 kg/m<sup>2</sup>) and Insulin-treated Type 2 Diabetes.

Obesity surgery·2026
Same author

Laparoscopic gastric pouch resection and esophago-jejunostomy after gastric bypass: indications and outcomes.

Langenbeck's archives of surgery·2026
Same author

A Practical Algorithm for Donor- and Recipient-site Selection in Vascularized Lymph Node Transfer in Extremity Lymphedema.

Plastic and reconstructive surgery. Global open·2026
Same author

SurfaceXR: Fusing Smartwatch IMUs and Egocentric Hand Pose for Seamless Surface Interactions.

IEEE transactions on visualization and computer graphics·2026

Related Experiment Video

Updated: Feb 26, 2026

Multimodality Diagnosis of Mesenteric Ischemia
05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

1.3K

Colon Perfusion Patterns During Colorectal Resection Using Visible Light Spectroscopy.

Henry Hoffmann1, Tarik Delko2, Philipp Kirchhoff2

  • 1Department of Surgery, University Hospital Basel, Spitalstrasse 21, 4031, Basel, Switzerland. henry.hoffmann@usb.ch.

World Journal of Surgery
|July 19, 2017
PubMed
Summary

Assessing colon perfusion during colorectal surgery reveals significant blood flow improvements. While abnormal perfusion was noted, it did not always lead to anastomotic leaks, suggesting complex healing dynamics.

More Related Videos

Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function
11:35

Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function

Published on: December 8, 2010

17.0K
An Open-Source Normothermic Perfusion System Designed for Research Scientists
11:23

An Open-Source Normothermic Perfusion System Designed for Research Scientists

Published on: July 18, 2025

1.3K

Related Experiment Videos

Last Updated: Feb 26, 2026

Multimodality Diagnosis of Mesenteric Ischemia
05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

1.3K
Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function
11:35

Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function

Published on: December 8, 2010

17.0K
An Open-Source Normothermic Perfusion System Designed for Research Scientists
11:23

An Open-Source Normothermic Perfusion System Designed for Research Scientists

Published on: July 18, 2025

1.3K

Area of Science:

  • Colorectal surgery
  • Surgical oncology
  • Gastroenterology

Background:

  • Anastomotic leakage remains a debated complication in colorectal surgery.
  • Bowel perfusion can be altered by surgical manipulation, limiting the value of single-point anastomosis assessment.
  • Dynamic assessment of bowel perfusion during surgery is proposed to understand its impact on outcomes.

Purpose of the Study:

  • To investigate the dynamics of colon perfusion during colorectal resection.
  • To evaluate the impact of perioperative changes in colon perfusion on anastomotic healing and surgical outcomes.

Main Methods:

  • Prospective cohort study of patients undergoing elective colorectal resection.
  • Colon perfusion assessed using visible light spectroscopy, measuring tissue oxygen saturation (StO2) in the colonic serosa.
  • Perfusion measurements taken before and after anastomosis creation during surgery.

Main Results:

  • Colon perfusion increased by an average of 5.9% StO2 during surgery (P < 0.001).
  • The incidence of abnormal perfusion (StO2 < 65%) decreased from 50% to 24% by the end of surgery.
  • Six patients (10%) developed anastomotic leaks; five had initial abnormal perfusion, and four had normal perfusion at the anastomosis.

Conclusions:

  • Colon perfusion significantly improves during colorectal surgery.
  • Impaired blood flow at the anastomosis alone may not be critical for anastomotic healing, as evidenced by patients with suboptimal perfusion who did not develop leaks.
  • Further research with larger cohorts is needed to fully elucidate the role of perioperative parameters in colon perfusion, anastomotic healing, and surgical outcomes.