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Initial testing of a pixelated silicon detector prototype in proton therapy.

Andrew J Wroe1,2, Grant McAuley2, Anthony V Teran2

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The dose magnifying glass (DMG), a novel pixelated silicon detector, accurately measures proton radiation fields for radiosurgery. This real-time dosimetry tool shows stable response and high spatial resolution, crucial for precise small-field treatments.

Keywords:
proton therapyradiosurgerysilicon diode radiation detectorssmall-field dosimetry

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Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Detector Technology

Background:

  • Advancements in radiation therapy require dosimetry tools with higher spatial resolution for small targets.
  • Current dosimetry methods need to evolve to meet the demands of precise radiation delivery.
  • Proton therapy offers conformal treatment but necessitates accurate real-time dosimetry for small fields.

Purpose of the Study:

  • To evaluate the performance of the dose magnifying glass (DMG) detector prototype for proton radiation dosimetry.
  • To assess the DMG's capabilities in measuring depth dose and lateral beam profiles in proton beams used for radiosurgery.
  • To compare DMG measurements with established dosimetry methods and Monte Carlo simulations.

Main Methods:

  • The DMG, a pixelated silicon detector, was tested using proton beams with energies and modulations typical for proton radiosurgery.
  • Depth dose profiles and lateral beam profiles were measured using the DMG.
  • Measurements were compared against a PTW parallel-plate ionization chamber, a PTW proton-specific dosimetry diode, EBT3 Gafchromic film, and Monte Carlo simulations.

Main Results:

  • The DMG demonstrated good agreement with Monte Carlo simulations, ionization chamber, and diode measurements for depth dose profiles.
  • Accurate Bragg peak location was determined by scanning the depth dose profile with the DMG.
  • Relative response of the DMG was within 2.5% of the dosimetry diode across tested proton energies and modulations.
  • Real-time lateral profile measurements showed high spatial resolution, with FWHM and FW90 within ±1 channel (0.1 mm) of reference data.

Conclusions:

  • The DMG is a valuable tool for real-time dosimetry in proton therapy, providing accurate depth dose profiles.
  • Its stable response across the spread-out Bragg peak and high spatial resolution enable precise 1D profile measurements of small radiation fields.
  • The detector minimizes partial volume averaging effects, enhancing accuracy in small-field dosimetry.