Acetylated Furostene Glycosides from Solanum gilo Fruits
Edwige Nana Tchoupang1, Christina Reder2, Sylvin Benjamin Ateba1
1Laboratory of Animal Physiology, Department of Animal Biology and Physiology, Faculty of Science, University of Yaounde 1, Yaounde, Cameroon.
Abstract:
In continuation of our work on a traditional mixture of spices called "Nkui", used in Cameroon for its influence on women's reproductive health, we investigated the chemical composition of Solanum gilo, one component of "Nkui". A methanolic extract was studied in detail. After dereplication of several known compounds, two furo-5-stene-derived saponin glycosides with acetylated sugar moieties were isolated. By extensive 1- and 2D NMR experiments and HR-MS and GC-MS methods, the structures were elucidated as 26-[(3‴,4‴,6‴-tri-O-acetyl)-β-D-glucopyranosyloxy]-22-hydroxyfurost-5-en-3β-yl-O-α-L-rhamnopyranosyl-(1″→2')-β-D-glucopyranoside (A) and 26-[(3‴,4‴,6‴-tri-O-acetyl)-β-D-glucopyranosyloxy]-22-hydroxyfurost-5-en-3β-yl-[O-α-L-rhamnopyranosyl-(1''''→4')-O-α-L-rhamnopyranosyl-(1″→2')]-β-D-glucopyranoside (B), both new natural compounds.
