Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Peripheral Artery Disease V: Postoperative Nursing Management

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...

Analgesia and Pain Management

Analgesia and Pain Management

Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Prognostic value of one-week postoperative pain for early recovery after total shoulder arthroplasty.

Shoulder & elbow·2026

Same author

Hand Deserve Better: global clinical consensus recommendations on surgical gloving practice.

The Journal of hospital infection·2026

Same author

The Utility of Baseline Prognostic Nutritional Index (PNI) and Functional Status Among Hip Fracture and Distal Femur Fracture Patients.

Archives of orthopaedic and trauma surgery·2026

Same author

Strong correlation of the Patient-Reported Outcomes Measurement Information System (PROMIS) upper extremity and Shoulder Arthroplasty Smart (SAS) score to legacy measures in shoulder arthroplasty patients.

JSES international·2025

Same author

Wound Irrigation Prior to Closure During Routine Upper-Extremity Surgery: Is There a Difference in Wound Complications?

Hand (New York, N.Y.)·2025

Same author

Correction: Best practices in telesurgery: framework and recommendations from the society of robotic surgery (SRS) for safe and effective implementation.

Journal of robotic surgery·2025

Search research articles

Related Experiment Video

Updated: Feb 26, 2026

Spontaneous and Evoked Measures of Pain in Murine Models of Monoarticular Knee Pain

Spontaneous and Evoked Measures of Pain in Murine Models of Monoarticular Knee Pain

Published on: February 22, 2019

Pain Control in Total Knee Arthroplasty.

Randa K Elmallah¹, Morad Chughtai², Anton Khlopas²

¹Department of Orthopaedic Surgery, University of Mississippi Medical Center, Jackson, Mississippi.

The Journal of Knee Surgery

|July 19, 2017

Summary

Effective total knee arthroplasty (TKA) pain management uses multimodal approaches, combining various analgesics and nerve blocks. Newer options like delayed-release anesthetics may further improve patient outcomes and reduce opioid reliance.

More Related Videos

Author Spotlight: Minimally Invasive Ultrasound-Guided Acupotomy in Knee Osteoarthritis Treatment

Author Spotlight: Minimally Invasive Ultrasound-Guided Acupotomy in Knee Osteoarthritis Treatment

Published on: April 26, 2024

Assessment of Knee Hyperalgesia in Mice using Pressure Application Measurement

Assessment of Knee Hyperalgesia in Mice using Pressure Application Measurement

Published on: June 13, 2025

Related Experiment Videos

Last Updated: Feb 26, 2026

Spontaneous and Evoked Measures of Pain in Murine Models of Monoarticular Knee Pain

Spontaneous and Evoked Measures of Pain in Murine Models of Monoarticular Knee Pain

Published on: February 22, 2019

Author Spotlight: Minimally Invasive Ultrasound-Guided Acupotomy in Knee Osteoarthritis Treatment

Author Spotlight: Minimally Invasive Ultrasound-Guided Acupotomy in Knee Osteoarthritis Treatment

Published on: April 26, 2024

Assessment of Knee Hyperalgesia in Mice using Pressure Application Measurement

Assessment of Knee Hyperalgesia in Mice using Pressure Application Measurement

Published on: June 13, 2025

Area of Science:

Orthopedics
Anesthesiology
Pain Management

Background:

Total knee arthroplasty (TKA) pain management is evolving with advancements in surgical techniques and pharmacology.
Current standards involve multimodal analgesia, including opioids, NSAIDs, gabapentinoids, nerve blocks, and periarticular injections.

Purpose of the Study:

To review current evidence-based treatment modalities for postoperative pain in TKA patients.
To forecast future changes in TKA pain management strategies.

Main Methods:

Systematic review of data on oral analgesics, periarticular injections, peripheral nerve blocks, multimodal regimens, and newer modalities.
Analysis of current and emerging pain management techniques for TKA.

Main Results:

Multimodal analgesic regimens targeting multiple pain pathways offer optimal pain control, rehabilitation, and patient satisfaction.
These regimens can significantly reduce opioid use and associated side effects.
Periarticular injections, particularly those with delayed-release local anesthetics, show promise for enhancing pain management post-TKA.

Conclusions:

Multimodal pain management is the cornerstone for effective TKA pain control, improving recovery and patient experience.
Emerging strategies like delayed-release local anesthetics represent a significant advancement in optimizing postoperative pain relief and minimizing opioid dependence.