AHRQ series on complex intervention systematic reviews-paper 3: adapting frameworks to develop protocols.

Mary Butler1, Richard A Epstein2, Annette Totten3

  • 1Minnesota EPC, University of Minnesota School of Public Health, 420 Delaware Street SE, Minneapolis, MN 55455, USA.

Summary

Developing a systematic review protocol for complex interventions requires adapting analytic frameworks. Modifications to population, intervention, comparators, and outcomes may be necessary, or alternative frameworks may be better suited.

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