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A reminder of Escherichia coli sepsis-induced reversible cardiomyopathy

Aung Naing Lin1, Atif Shaikh2,3, Sithu Lin1

  • 1Department of Internal Medicine, The Brooklyn Hospital Center, Brooklyn, New York, USA.

BMJ Case Reports
|July 20, 2017
PubMed

Insights

Sepsis-induced cardiomyopathy (SICM) can cause severe heart dysfunction but is often reversible. This case highlights the potential benefit of beta-blockers in recovery after sepsis.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Cardiomyopathy encompasses myocardial diseases causing mechanical or electrical dysfunction.
  • Sepsis-induced cardiomyopathy (SICM) is a potentially reversible condition following sepsis or septic shock.
  • The precise mechanisms and mortality impact of SICM remain incompletely understood.

Observation:

  • A 63-year-old woman presented with acute dyspnea and orthopnea after consuming contaminated food.
  • Initial evaluation revealed severely reduced left ventricular ejection fraction (<20%) consistent with SICM.
  • Cardiac catheterization confirmed non-obstructive coronary arteries.

Findings:

  • The patient's left ventricular ejection fraction normalized to 57% within 10 days post-sepsis recovery.
  • No specific therapies for SICM reversal are currently established.
  • Beta-blocker initiation post-septic shock recovery appeared beneficial.

Implications:

  • This case underscores the reversible nature of SICM and its potential for rapid recovery.
  • Early recognition and supportive care are crucial for managing SICM.
  • Further research into targeted therapies and the role of beta-blockers in SICM is warranted.
Keywords:
Cardiovascular systemInfectionsRespiratory system

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