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Broadly expressed repressors integrate patterning across orthogonal axes in embryos

Theodora Koromila1, Angelike Stathopoulos2

  • 1Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125.

Proceedings of the National Academy of Sciences of the United States of America
|July 20, 2017
PubMed
Summary

Ubiquitously expressed repressors like Runt (Run) and Suppressor of Hairless [Su(H)] transiently silence enhancers, controlling gene expression timing. This mechanism coordinates patterning along both anterior-posterior and dorsal-ventral axes in the Drosophila embryo.

Keywords:
RuntSu(H)embryonic patterningenhancerstranscriptional repressor

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