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Surgical Model for Single-Staged Tissue-Engineered Urothelial Tubes in Minipigs

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Exstrophy Bladder - Reconstruction or Diversion for the Underprivileged.

Yogesh Kumar Sarin¹, Virender Sekhon²

¹Department of Pediatric Surgery, Maulana Azad Medical College, New Delhi, 110002, India. yksarin@gmail.com.

Indian Journal of Pediatrics

|July 20, 2017

Summary

This summary is machine-generated.

Yogesh's cystorectostomy offers a single-stage solution for bladder exstrophy epispadias complex, achieving total urinary continence and preserving upper tract function. This approach is ideal for resource-poor settings, improving patient quality of life.

Keywords:

Bladder exstrophy Developing countries Epispadias Health services accessibility Urinary incontinence

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Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

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Area of Science:

Pediatric Urology
Surgical Reconstruction
Congenital Anomalies

Background:

Bladder exstrophy epispadias complex management has evolved, but complications and variable outcomes persist.
Resource-poor settings present unique challenges, necessitating simplified surgical approaches.
Current methods often require staged procedures, bladder augmentation, and clean intermittent catheterization, impacting quality of life.

Purpose of the Study:

To evaluate the efficacy of Yogesh's cystorectostomy as a primary surgical option for bladder exstrophy epispadias complex.
To assess the feasibility of a single-stage procedure for achieving urinary continence and preserving upper tract function in resource-limited environments.
To determine patient and parental satisfaction and impact on quality of life.

Main Methods:

Yogesh's cystorectostomy, a modification of the Heitz-Boyer-Hovelacque procedure, involves direct anastomosis of the bladder plate to the recto-sigmoid pouch.
Ureters are not mobilized from their original location during the procedure.
Short-term follow-up assessments focused on urinary continence, upper tract function, and patient/parental satisfaction.

Main Results:

All patients achieved total urinary continence within months of the procedure.
Upper urinary tract functions were well preserved post-operatively.
High levels of parental and patient satisfaction were reported, indicating an improved quality of life.

Conclusions:

Yogesh's cystorectostomy is an effective single-stage surgical option for bladder exstrophy epispadias complex, particularly in resource-poor settings.
The procedure facilitates primary urinary continence and preserves upper tract integrity.
This technique offers a viable alternative to complex, multi-stage reconstructions, enhancing patient outcomes and quality of life.