Related Experiment Video
Updated: Feb 26, 2026
Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
Published on: March 25, 2022
Effectiveness of a novel highly flexible-tip guidewire on selective biliary cannulation compared to conventional
Jin-Seok Park1, Seok Jeong1, Don Haeng Lee1
1Digestive Disease Center, Department of Internal Medicine, Inha University School of Medicine, Incheon, South Korea.
Background And Aim:
Endoscopic access to the common bile duct remains difficult in 10% of cases undergoing endoscopic retrograde cholangiopancreatography (ERCP). In the current study, we evaluated the effectiveness of a stiff-shaft and flexible-tip guidewire (Visiglide2® ) for selective biliary access.
Methods:
We conducted a prospective, randomized controlled study in a single center involving patients with a naïve papilla who required biliary cannulation. We randomly allocated the patients to the Visiglide 2 group (group V) or to the conventional guidewire group (group C). Primary success rate of biliary cannulation, cannulation time, number of papillary attempts, number of pancreatic duct cannulations, total procedure time and final success rate were recorded during the endoscopic procedure.
Results:
Total of 100 patients were enrolled and assigned to groups V (n = 50) and C (n = 50). Primary selective biliary cannulation of group V tended to show a higher success rate than that of group C (group V, 96% (48/50); group C, 86% (43/50); P = 0.08). Final success rate for biliary cannulation was 100% in both groups. Mean times for biliary cannulation were 174.9 s for group V and 363.5 s for group C (P = 0.04). Number of papillary attempts for cannulation was significantly fewer in group V (1.84) than in group C (3.44; P < 0.01).
Conclusion:
Use of Visiglide 2 guidewire might facilitate selective biliary cannulation compared to conventional guidewire in terms of reducing cannulation time and papilla attempts.
