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Related Experiment Video

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Plasmonic Trapping and Release of Nanoparticles in a Monitoring Environment

Plasmonic Trapping and Release of Nanoparticles in a Monitoring Environment

Published on: April 4, 2017

Topographically Flat Nanoplasmonic Sensor Chips for Biosensing and Materials Science.

Ferry Anggoro Ardy Nugroho¹, Rickard Frost¹, Tomasz J Antosiewicz^1,2

¹Department of Physics, Chalmers University of Technology , 412 96 Göteborg, Sweden.

|July 20, 2017

Summary

This study introduces flat nanoplasmonic sensor chips fabricated using wafer-scale nanolithography, overcoming surface topography issues in traditional sensors for improved bio- and chemosensing applications.

Keywords:

avidin adsorption b-BSA specific binding flat topography nanoplasmonic sensing (NPS)polymer glass transition supported lipid bilayer formation surface corrugation

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Area of Science:

Materials Science
Nanotechnology
Surface Science

Background:

Nanoplasmonic sensors utilize noble metal nanoparticles on dielectric supports, resulting in inherent surface topography (10-100 nm corrugations).
Surface topography can significantly influence interactions between solids, fluids, nanoparticles, and (bio)molecules on sensor surfaces.
This influence can impact the performance of bio- and chemosensing applications.

Purpose of the Study:

To develop a wafer-scale nanolithography fabrication method for nanoplasmonic sensor chips.
To create sensor chips that are high-temperature compatible, chemically inert, topographically flat, and laterally homogeneous.
To evaluate the sensing performance of these novel flat sensors compared to traditional corrugated ones.

Main Methods:

Wafer-scale nanolithography for fabricating flat nanoplasmonic sensor chips.
Fabrication of high-temperature compatible and chemically inert sensor surfaces.
Comparative sensing performance analysis against traditional nanoplasmonic sensors with surface corrugations.

Main Results:

Demonstrated successful fabrication of flat, homogeneous nanoplasmonic sensor chips.
Quantified the film-thickness dependence of glass transition temperature in poly(methyl methacrylate) thin films.
Characterized adsorption and binding kinetics of avidin-biotinylated bovine serum albumin and analyzed supported lipid bilayer formation on SiO2 surfaces.

Conclusions:

Flat nanoplasmonic sensor chips fabricated via nanolithography offer a viable alternative to traditional corrugated sensors.
The developed fabrication approach enables high-temperature compatible and chemically inert sensing platforms.
These flat sensors show promising performance for various bio- and chemosensing applications, including thin film analysis, protein interactions, and lipid bilayer studies.