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Recent advances in gossypol derivatives and analogs: a chemistry and biology view

Yuzhi Lu1, Jun Li1, Chun-E Dong1

  • 1Hubei Province Engineering & Technology Research Center for Fluorinated Pharmaceuticals, Key Laboratory of Combinatorial Biosynthesis & Drug Discovery, Ministry of Education, Wuhan University School of Pharmaceutical Sciences, Wuhan 430071, China.

Future Medicinal Chemistry
|July 20, 2017
PubMed

Keywords:
Bcl-2 inhibitorantiapoptoticantitumorgossypolgossypol derivativesnatural product chemistrypolyphenolsscaffold hoppingstructure–activity relationshipsynthetic chemistry

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