Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bioinspired Zr-Cu Dual Sites Regulate Hydrogen Peroxide Heterolysis for Naked-Eye Glyphosate Sensing.

ACS sensors·2026
Same author

Bi-Doped Pd Aerogels with Tensile-Strain-Induced Cascade Orbital Hybridization Boost H<sub>2</sub>O<sub>2</sub> Selective Activation for Efficient Pesticide Distinction.

Research (Washington, D.C.)·2026
Same author

Regulating the Adsorbed Hydrogen Coverage for a Good Trade-Off between Hydrogen Evolution Activity and Electrochemiluminescence Performance.

Analytical chemistry·2026
Same author

Toward Bioreceptor-Free Nanozyme Sensing: Matched Interaction and Ligand-Modulated Phosphatase-Mimetic Activity Enable Anti-Interference and Sensitive Detection of Quinolones in Dairy Products.

Analytical chemistry·2026
Same author

Correction to "Single-Atom Ce-Doped Metal Hydrides with High Phosphatase-like Activity Amplify Oxidative Stress-Induced Tumor Apoptosis".

ACS nano·2026
Same author

Reactive Hydrogen-Mediated Peroxydisulfate Activation for Boosting Carbon Nitride Electrochemiluminescence.

Analytical chemistry·2026
Same journal

Double-Strand Gated Biosensor for Ultrasensitive T4 PNK Detection via λ-Exonuclease-Driven Background Suppression and Dimer G-Triplex Signal Amplification.

ACS sensors·2026
Same journal

Junction-Amplified Porous SnO<sub>2</sub>-Co<sub>3</sub>O<sub>4</sub> Nanospheres for ppb-Level Low-Temperature Acetone Detection and Wearable-Integrated Breath Monitoring.

ACS sensors·2026
Same journal

A Wearable Earplug-Shaped Piezoresistive Sensor Based on Ear Canal Deformation for the Screening of Temporomandibular Joint Motion Abnormalities.

ACS sensors·2026
Same journal

A Triple-Signal Output Lateral Flow Platform Leveraging CRISPR/Cas12a and Nanozyme Cascades for Ultra-Sensitive Aflatoxin B1 Detection.

ACS sensors·2026
Same journal

Dual-Active-Site Synergy in Metal-Organic Framework-Derived Er:CeO<sub>2</sub>/ZnO Nanofibers Enabling Humidity-Independent Triethylamine Detection at Room Temperature.

ACS sensors·2026
Same journal

A Point-of-Care System for the Quantification of Small-Molecule Drugs in Blood.

ACS sensors·2026
See all related articles

Related Experiment Video

Updated: Jun 18, 2026

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
12:31

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay

Published on: February 28, 2015

15.7K

Versatile Barometer Biosensor Based on Au@Pt Core/Shell Nanoparticle Probe.

Qiangqiang Fu1, Ze Wu, Dan Du1

  • 1School of Mechanical and Materials Engineering, Washington State University , Pullman, Washington 99164, United States.

ACS Sensors
|July 21, 2017
PubMed
Summary
This summary is machine-generated.

We developed a novel barometer-based biosensor using gold-platinum nanoparticles for detecting various targets like cancer markers and environmental contaminants. This portable, cost-effective device offers sensitive and specific results, validated in real-world samples.

Keywords:
aptasensorsbarometer-based biosensorscore−shell Au@Pt nanoparticlesimmunosensorsnanocatalysts

More Related Videos

Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis
07:30

Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis

Published on: March 7, 2018

8.0K
Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging
06:19

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging

Published on: June 9, 2023

2.1K

Related Experiment Videos

Last Updated: Jun 18, 2026

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
12:31

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay

Published on: February 28, 2015

15.7K
Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis
07:30

Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis

Published on: March 7, 2018

8.0K
Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging
06:19

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging

Published on: June 9, 2023

2.1K

Area of Science:

  • Biomedical Engineering
  • Analytical Chemistry
  • Nanotechnology

Background:

  • High global demand exists for sensitive, portable, user-friendly, and cost-effective biosensors.
  • Existing biosensing technologies often face limitations in portability, cost, or complexity.

Purpose of the Study:

  • To introduce a novel barometer-based biosensor for detecting a broad range of targets.
  • To demonstrate the versatility of the biosensor for detecting biomarkers and environmental contaminants.

Main Methods:

  • Utilized core-shell Au@Pt nanoparticles (Au@PtNPs) as bioassay probes to catalyze hydrogen peroxide decomposition and oxygen generation.
  • Measured pressure changes in a sealed chamber using a portable barometer to quantify oxygen release.
  • Developed barometer-based immunosensors for carcinoembryonic antigen (CEA) and ractopamine (Rac), and aptasensors for thrombin and mercury ions (Hg2+).
  • Integrated smartphone software for data analysis, storage, and wireless transmission.

Main Results:

  • Achieved linear detection ranges for CEA (0.025-1.6 ng/mL), Rac (0.0625-4 ng/mL), thrombin (4-128 U/L), and Hg2+ (0.25-16 ng/mL).
  • Demonstrated low detection limits: 0.021 ng/mL for CEA, 0.051 ng/mL for Rac, 2.4 U/L for thrombin, and 0.22 ng/mL for Hg2+.
  • Confirmed high specificity and validated the biosensor's performance in real samples (serum, urine, river water), showing consistency with traditional methods.

Conclusions:

  • The developed barometer-based biosensor is sensitive, portable, user-friendly, and cost-effective.
  • The biosensor platform demonstrates wide applicability for detecting diverse analytes in various sample matrices.
  • This technology holds significant potential for point-of-care diagnostics and environmental monitoring.