Related Experiment Video
Updated: Feb 26, 2026
08:40
Establishment and Characterization of UTI and CAUTI in a Mouse Model
Published on: June 23, 2015
21.1K
Trends in Antibiotic Resistance in Urologic Practice
Hala Kandil1, Emma Cramp2, Tejal Vaghela3
1Microbiology Department, West Hertfordshire Hospitals NHS Trust, Watford, UK.
European Urology Focus
|July 21, 2017
Summary
Antimicrobial resistance is rising in urology, challenging treatment of Gram-negative infections. Understanding local resistance patterns and guidelines is crucial for effective antibiotic selection.
Area of Science:
- Urology
- Infectious Diseases
- Pharmacology
Background:
- Rising antimicrobial resistance (AMR) poses a significant global health threat.
- Enterobacteriaceae and Gram-negative uropathogens show increasing resistance.
- Urologic practice faces particular challenges due to AMR.
Purpose of the Study:
- To review current trends in antibiotic resistance within urologic practice.
- To summarize emerging resistance patterns and their impact on urologic infections.
- To discuss current guidelines and key antibiotics for managing resistant uropathogens.
Main Methods:
- Review of current European trends in Gram-negative uropathogen resistance.
- Analysis of resistance patterns across multiple drug classes.
- Synthesis of information on emerging resistance and treatment guidelines.
Main Results:
- Gram-negative uropathogens exhibit resistance to beta-lactams, aminoglycosides, fluoroquinolones, and carbapenems.
- Multiple drug resistance is common in pathogens causing urologic infections.
- New antibiotics are in development to combat resistant strains.
Conclusions:
- Increasing antimicrobial resistance presents a significant challenge for urologic treatment and prophylaxis.
- Antibiotic selection must consider patient risk factors for multidrug resistance.
- Local microbial prevalence and resistance profiles are essential for guiding antimicrobial therapy.
Keywords:
Acute pyelonephritisAntimicrobial resistanceCatheter-associated urinary tract infectionComplicated urinary tract infectionProstatitisTransurethral prostate biopsyUncomplicated urinary tract infectionUrologic infectionsMore Related Videos
Related Concept Videos
01:30Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
367
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
367
01:26Urine Studies II: Urine Culture and Sensitivity Test
1.5K
A urine culture and sensitivity test is a diagnostic procedure used to identify urinary tract bacterial infections and determine the most effective antibiotics for treatment. This test is generally preferred when a patient shows manifestations of a urinary tract infection, such as frequent or painful urination, cloudy or foul-smelling urine, or lower abdominal pain.Purpose of the TestThe primary goals of a urine culture and sensitivity test are to:Determine the specific bacteria causing the...
1.5K
01:30Development of Antibiotic Resistance
1.7K
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
1.7K
00:57Antibiotic Selection
60.9K
Overview
60.9K
01:25Urinary Tract Infection II: Pathophysiology
892
The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
892
01:26Urinary Tract Infection I: Introduction
830
Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
830