Active Surveillance for Small Renal Masses in Young Patients

Giovanni Cacciamani1, Carlos Fay2, Daniel Park2

  • 1Section of Robotic & Laparoscopic Surgery, Catherine & Joseph Aresty Department of Urology, USC Institute of Urology, University of Southern California, Los Angeles, CA, USA; Department of Urology, University of Verona, Azienda Universitaria Integrata, Verona, Italy.

Insights

Active surveillance is appropriate for elderly patients with small renal masses (SRMs) due to high comorbidity risks. However, evidence supporting this approach in younger individuals is currently insufficient.

Area of Science:

  • Urology
  • Oncology
  • Nephrology

Background:

  • Small renal masses (SRMs) are increasingly detected.
  • Active surveillance is a management option for SRMs.
  • Patient selection is crucial for active surveillance protocols.

Purpose of the Study:

  • To evaluate the appropriateness of active surveillance for SRMs.
  • To identify patient populations suitable for active surveillance.
  • To highlight the lack of evidence for active surveillance in specific demographics.

Main Methods:

  • Review of current literature on SRM management.
  • Analysis of risk-benefit profiles for active surveillance.
  • Comparative assessment of oncologic versus comorbidity risks.

Main Results:

  • Active surveillance is recommended for elderly and infirm patients with SRMs.
  • Comorbidity risks in these populations often outweigh oncologic risks.
  • Limited evidence exists to support active surveillance for SRMs in younger patients.

Conclusions:

  • Active surveillance for SRMs is appropriate in select elderly and infirm patients.
  • Careful patient selection is paramount for successful active surveillance.
  • Further research is needed to establish the role of active surveillance in younger individuals with SRMs.

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