Related Experiment Video
Updated: Jul 10, 2026

A Melanoma Patient-Derived Xenograft Model
Published on: May 20, 2019
Malignant melanoma misdiagnosed as diabetic foot ulcer: A case report
Wei Gao1, Dawei Chen, Xingwu Ran
1Department of Endocrinology and Metabolism Health Management Center Diabetic Foot Care Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Rationale:
Acral lentiginous melanoma (AML) does not exhibit the classic signs of malignant melanoma. ALM is frequently misdiagnosed because of its unusual sites and atypical clinical morphologies, which lead to poor prognosis.
Patient Concerns:
A female patient aged 78 years was presented to our center with two ulcers on her right foot. Diabetic foot ulcer was considered as the primary diagnosis. The ulcers failed to improve after 2 weeks' therapy.
Diagnoses:
An incisional biopsy of the lesion revealed malignant melanoma.
Interventions:
The patient received wide excision, skin grafting as well as biotherapy.
Outcomes:
The lesion was healed and no other metastasis has been founded until now.
Lessons:
Clinicians must maintain a high level of suspicion in distinguishing malignant melanoma from other more benign skin lesions of the foot. The need for early biopsy of ulcer, even when clinical suspicion is low, can not be overemphasized. Only in this way can we reduce misdiagnosis rate and improve survival rate in patients with foot ulcer.
More Related Videos
04:09Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
Published on: March 3, 2023
09:38Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity
Published on: January 31, 2025
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis
Complications of Diabetes Mellitus
Diabetic Foot Ulcer
Diabetic Retinopathy
Diabetic Neuropathy