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Francesco Vierucci1, Marta Del Pistoia2, Emioli Randazzo2

  • 1S.C. Pediatria, Ospedale San Luca, Lucca, Italy.

Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [And] German Diabetes Association
|July 21, 2017
PubMed
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Vitamin D deficiency presents a spectrum of health issues, from asymptomatic cases to rickets and osteomalacia. Immigrant families are particularly at risk, necessitating family-wide screening for vitamin D deficiency.

Area of Science:

  • Nutritional Science
  • Pediatric Endocrinology
  • Public Health

Background:

  • Vitamin D deficiency is a significant global health concern impacting children and adolescents.
  • It manifests in diverse clinical presentations, underscoring the need for comprehensive understanding.

Observation:

  • A 10-month-old infant of Senegalese origin presented with nutritional rickets, indicative of vitamin D deficiency.
  • Family members, including the mother and four brothers, were evaluated due to shared risk factors.

Findings:

  • Three brothers had asymptomatic vitamin D deficiency, two with secondary hyperparathyroidism.
  • The fourth brother exhibited nutritional rickets, and the mother presented with osteomalacia.
  • None of the family members had received vitamin D supplementation.

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Implications:

  • Vitamin D deficiency exists on a continuum from asymptomatic to severe bone disease like rickets and osteomalacia.
  • Immigrant populations face elevated risks of vitamin D deficiency across all age groups.
  • Screening all family members is crucial when symptomatic vitamin D deficiency is identified.