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Updated: Feb 26, 2026

Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy
Published on: August 22, 2018
Classification of skin phenotypes caused by diabetes mellitus using complex scattering parameters in the
Fabian Dornuf1, Pedro Martín-Mateos2, Blanca Duarte3,4
1Physics Institute, Goethe University Frankfurt am Main, 60438, Frankfurt am Main, Germany. dornuf@physik.uni-frankfurt.de.
Abstract:
The pathological skin phenotype caused by hyperglycemia is an important indicator for the progress of diabetes mellitus. An early detection of diabetes assures an early intervention to regulate the carbohydrate metabolism. In this publication a non-invasive detection principle based on the measurement of complex scattering parameters in the millimeter-wave frequency range is presented. The measurement principle provides evidence of the applicability for the identification of different glycemic states in animal models. The method proposed here can be used to predict diabetes status in animal models and is interesting for application on humans in view of safeness of millimeter-wave radiation. Furthermore the complex scattering parameters give important information about the anatomic varieties between the analyzed skin samples of the different mice strains. In contrast to other methods, our approach is less sensitive to skin variations between animals.
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