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Review of Infectious Etiology of Acute Pancreatitis
Prashanth Rawla1, Sathyajit S Bandaru2, Anantha R Vellipuram3
1Department of Internal Medicine, Monmouth Medical Center, Long Branch, NJ, USA.
Abstract:
While gallstones and alcoholism are widely known to be the most common causative agents of acute pancreatitis, about 10% of cases are thought to be caused by infectious microorganisms. These microorganisms include viruses (e.g. mumps, Coxsackie B, and hepatitis), bacteria (e.g. Mycoplasma pneumoniae and leptospirosis), and parasites (e.g. Ascaris lumbricoides, Fasciola hepatica, and hydatid disease). Each organism causes acute pancreatitis through diverse mechanisms. The review is primarily conducted in an attempt to provide a better understanding of the possibility of acute pancreatitis presenting as a complication relating to these organisms, and the aim is to guide future diagnoses, management, and predictions of complications.
Insights
Infectious microorganisms like viruses, bacteria, and parasites can cause acute pancreatitis, a condition often attributed to gallstones or alcohol. Understanding these infectious causes is key for diagnosis and management.
Area of Science:
- Infectious diseases
- Gastroenterology
- Microbiology
Background:
- Gallstones and alcoholism are primary causes of acute pancreatitis.
- Approximately 10% of acute pancreatitis cases stem from infectious agents.
Purpose of the Study:
- To explore the role of infectious microorganisms in acute pancreatitis.
- To enhance understanding of pancreatitis as a complication of infections.
- To guide future diagnosis, management, and complication prediction.
Main Methods:
- Literature review focusing on infectious causes of acute pancreatitis.
- Analysis of diverse mechanisms by which microorganisms induce pancreatitis.
Main Results:
- Identified viruses (mumps, Coxsackie B, hepatitis), bacteria (Mycoplasma pneumoniae, leptospirosis), and parasites (Ascaris lumbricoides, Fasciola hepatica, hydatid disease) as causative agents.
- Highlighted varied pathogenic mechanisms employed by these microorganisms.
Conclusions:
- Infectious etiologies represent a significant, though less common, cause of acute pancreatitis.
- Further research into these infectious links can improve clinical outcomes.
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