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Nickel-resistant bacteria isolated in human microbiome.

E A Lusi1, T Patrissi2, P Guarascio3

  • 1St Vincent Health Care Group, UCD, Dublin, Ireland.

New Microbes and New Infections
|July 21, 2017
PubMed
Summary

Nickel-resistant bacteria, previously found only in polluted environments, have now been identified in human samples. This discovery reveals the presence of heavy-metal-tolerant bacteria within the human body, necessitating further research.

Keywords:
Human microbiomeNickelNickel allergyNickel-resistant bacteriaOverweight

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Area of Science:

  • Microbiology
  • Environmental Science
  • Human Health

Background:

  • Nickel-resistant bacteria are typically found in industrial-contaminated soils and wastewaters.
  • The presence and implications of such bacteria in human samples remain largely unexplored.

Purpose of the Study:

  • To investigate the potential isolation of nickel-resistant bacteria from human samples.
  • To characterize these bacterial strains using both phenotypic and genetic methods.

Main Methods:

  • Isolation of anaerobic bacterial strains from human samples.
  • Cultivation of bacteria in the presence of high nickel concentrations.
  • Identification using phenotypic and genetic techniques, including sequence deposition in NCBI.

Main Results:

  • Successfully isolated nickel-resistant bacterial strains from human samples.
  • These strains exhibit anaerobic growth and tolerance to high nickel levels.
  • Bacterial sequences have been cataloged in the NCBI database.

Conclusions:

  • Human samples can harbor diverse nickel-resistant bacteria.
  • These findings highlight the need for further investigation into the role and impact of heavy-metal-tolerant bacteria in humans.