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Updated: Feb 26, 2026
Alternative In Vitro Methods for the Determination of Viral Capsid Structural Integrity
Published on: November 16, 2017
Strategies and methods for the detection and identification of viral vectors
Thorsten Stellberger1, Nina Koehler1, Anna Dinkelmeier1
1Bavarian Health and Food Safety Authority (LGL), Veterinaerstr. 2, 85764, Oberschleissheim, Germany.
Abstract:
The production and application of viral vectors are frequently performed genetic engineering operations. HIV-1-based lentiviral vectors, AAV2-based, and adenoviral vectors are amongst the most abundant viral vectors utilized for gene delivery. They are generally classified into risk group 1 or 2 (according to EU directive 2000/54/EC on the protection of workers from risks related to exposure to biological agents at work).
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