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Change in skin properties over the first 10 years of life: a cross-sectional study

Fanqi Kong1,2, Carlos Galzote3, Yuanyuan Duan4

  • 1Johnson & Johnson AP Skin Testing Center, Shanghai, China. fkong@its.jnj.com.

Archives of Dermatological Research
|July 21, 2017
PubMed

Insights

This study found that younger children have softer, smoother skin than older children, with a more permeable skin barrier that matures by age five. Adult women showed higher skin moisture levels than children.

Area of Science:

  • Dermatology
  • Pediatric dermatology
  • Skin physiology

Background:

  • Child skin differs significantly from adult skin.
  • Understanding pediatric skin development is crucial for targeted skincare and treatment.
  • Previous research has not fully characterized age-related skin changes in Chinese children.

Purpose of the Study:

  • To investigate and characterize skin properties in healthy Chinese children aged 1-10 years.
  • To compare pediatric skin characteristics with those of their mothers.
  • To assess the maturation of the skin barrier in children.

Main Methods:

  • Cross-sectional study involving 1-10-year-old children and their mothers.
  • Clinical assessments included skin softness, smoothness, erythema, edema, rash, dryness, and scaling.
  • Instrumental evaluations measured transepidermal water loss, moisture content, and water-holding capacity.

Main Results:

  • Clinical evaluations showed decreased skin softness, smoothness, and overall condition with increasing age in children.
  • Children exhibited a more permeable skin barrier, reaching adult levels around age 5.
  • Mothers generally had higher skin moisture content than their children.

Conclusions:

  • Pediatric skin matures significantly between ages 1 and 10, with younger children having superior skin condition.
  • The skin barrier in children becomes less permeable and more mature with age.
  • Findings highlight age-specific differences in skin physiology between children and adults.

Keywords:
AdultChildrenSkin barrierSkin conditionTransepidermal water lossWater handling

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