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Updated: Feb 26, 2026

In Vivo Imaging Systems IVIS Detection of a Neuro-Invasive Encephalitic Virus
Published on: December 2, 2012
California Serogroup Virus Infection Associated with Encephalitis and Cognitive Decline, Canada, 2015
Abstract:
California serogroup (CSG) viruses, such as Jamestown Canyon and snowshoe hare viruses, are mosquitoborne pathogens that cause febrile illness and neurologic disease. Human exposures have been described across Canada, but infections are likely underdiagnosed. We describe a case of neuroinvasive illness in a New Brunswick, Canada, patient infected with a CSG virus.
Insights
California serogroup (CSG) viruses cause serious illness. A New Brunswick case highlights potential underdiagnosis of these mosquito-borne pathogens in Canada.
Area of Science:
- Arbovirology
- Infectious Diseases
- Neurology
Background:
- California serogroup (CSG) viruses are mosquito-borne pathogens.
- CSG viruses, including Jamestown Canyon virus and snowshoe hare virus, can cause febrile and neurologic illnesses.
Observation:
- Human CSG virus exposures are reported throughout Canada.
- Infections are likely underdiagnosed.
Findings:
- This study details a case of neuroinvasive illness in a New Brunswick, Canada patient.
- The patient was infected with a CSG virus.
Implications:
- This case underscores the importance of recognizing CSG virus infections in Canada.
- Increased awareness and diagnostic efforts may be needed for these underdiagnosed arboviruses.
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