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Published on: September 13, 2022
Outcomes of miniaturized percutaneous nephrolitotomy in infants: single centre experience
Eyyup Sabri Pelit1, Bülent Kati1, Cengiz Çanakci2
1Department of Urology, Harran University Faculty of Medicine, Sanliurfa, Turkey.
Insights
Mini-percutaneous nephrolithotomy (Mini-PNL) is a safe and effective treatment for kidney stones in infants under 3 years old. This procedure offers a high stone-free rate with minimal complications, making it a viable option for pediatric urolithiasis.
Area of Science:
- Pediatric Urology
- Minimally Invasive Surgery
- Nephrolithiasis Management
Background:
- Kidney stones (renal lithiasis) in infants (<3 years) present unique management challenges.
- Limited data exists on the efficacy and safety of minimally invasive techniques in this age group.
- Percutaneous nephrolithotomy (PNL) has been adapted for pediatric use, with Mini-PNL emerging as a potentially less invasive option.
Purpose of the Study:
- To evaluate the safety and efficacy of Mini-PNL for treating kidney stones in infants aged less than 3 years.
- To report outcomes from one of the largest series of Mini-PNL in this specific pediatric population.
- To assess the stone-free rate, operative time, complications, and hospitalization duration associated with Mini-PNL in infants.
Main Methods:
- Retrospective review of medical records for 74 infant patients who underwent Mini-PNL for renal stones (May 2012 - April 2016).
- Pre-operative evaluation included radiography, ultrasound, CT, and/or IVU.
- Analysis of pre-operative, intra-operative, and post-operative data, including stone size, operative time, and complications.
Main Results:
- 74 infants (mean age 21.5 months) with mean stone size of 22.0 mm were treated.
- A 17 Fr rigid pediatric nephroscope and pneumatic lithotripsy were utilized.
- The stone-free rate was 84.7% at 1 month post-operation.
- Mean operative time was 74 minutes, with a mean fluoroscopy time of 4.3 minutes.
- No major complications (Clavien IV-V) were observed; 15.3% required auxiliary procedures.
Conclusions:
- Mini-PNL, utilizing pneumatic intracorporeal lithotripsy, is a safe and effective treatment modality for pediatric kidney stones in infants.
- The procedure demonstrates a high stone-free rate and a low incidence of significant complications in this young patient cohort.
- Mini-PNL represents a valuable minimally invasive surgical option for managing urolithiasis in infants.
Objectives:
The present study was aim to evaluate the safety and efficacy of Mini-PNL to treat kidney stones in patients aged <3 years. This is the one of the largest series in the literature in this age group of patients.
Material And Methods:
From May 2012 to April 2016, the medical records of 74 infant patients who underwent mini-PNL for renal stones were reviewed retrospectively. All infants were evaluated with the plain abdominal radiograph, urinary ultrasound, noncontrast computerized tomography and/or intravenous urogram. Pre-operative, intraoperative and post-operative data were analyzed.
Results:
A total of 74 infant (42 male, 32 female) with a mean age 21.5±8.2 (10-36) months were included in this study. The mean size of the stones was 22.0±5.9 (14-45) mm. A 17 Fr rigid pediatric nephroscope with a pneumatic intracorporeal lithotripsy were used through 20-22 Fr access sheath. The stone-free rate was 84.7% at 1 month after the operation. Mean operative time was 74.0 (40-140) min. Mean fluoroscopy screening time was as 4.3(3.1-8.6) min. Average hospitalization time was 3.8 (2-9) day. Auxiliary procedures were performed to 11(15.3%) patients (7 extracorporeal shock wave lithotripsy, 3 re- percutaneous nephrolitotomy, 1 retrograde intrarenal surgery). No major complication classified as Clavien IV-V observed in study group.
Conclusions:
Mini-PNL with pneumatic intracorporeal lithotripsy can be performed safely and effectively to manage kidney stones in infants with high stone free rate and low complications.
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