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Related Experiment Video

Updated: Feb 26, 2026

Single Particle Cryo-Electron Microscopy: From Sample to Structure

Single Particle Cryo-Electron Microscopy: From Sample to Structure

Published on: May 29, 2021

Focal cryotherapy: step by step technique description.

Cristina Redondo¹, Victor Srougi², José Batista da Costa³

¹Hospital Universitario de Getafe - Servicio de Urología, Getafe, Spain.

International Braz J Urol : Official Journal of the Brazilian Society of Urology

|July 21, 2017

Summary

This summary is machine-generated.

Focal cryotherapy offers a minimally invasive approach for localized prostate cancer (PCa), demonstrating good cancer control and functional outcomes. This video details the step-by-step procedure for treating anterior PCa.

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Area of Science:

Urology
Oncology
Minimally Invasive Surgery

Background:

Focal cryotherapy is an emerging treatment for localized prostate cancer (PCa).
This video demonstrates the procedural steps for focal cryotherapy.
The procedure is suitable for favorable and localized PCa, particularly in the anterior prostate.

Observation:

The procedure involves trans-rectal ultrasound guidance for precise cryoprobe placement.
Cryotherapy utilizes extreme cold (-40°C) via argon gas to induce tumor cell lysis, followed by helium gas thawing.
A urethral warming catheter is used to protect the urethra during the procedure.

Findings:

Biochemical disease-free survival rates range from 71-93% at 9-70 months follow-up.
Incontinence rates are reported between 0-3.6%.
Erectile dysfunction rates are between 0-42%.

Implications:

Focal cryotherapy is a feasible treatment option for anterior prostate cancer.
It may offer reduced morbidity compared to whole-gland treatments.
This technique shows potential for good cancer control and improved functional outcomes.