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Updated: Feb 26, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Structural Changes of the Macula on Optical Coherence Tomography after Vitrectomy for Proliferative Diabetic
Jong Chan Im1, Jong Ho Kim, Dong Ho Park
1Department of Ophthalmology, Samsung Changwon Hospital, Sungkyunkwan University, Changwon, South Korea.
Purpose:
This study aimed to evaluate the relationship between macular structural changes and visual prognosis after pars plana vitrectomy (PPV) for proliferative diabetic retinopathy.
Methods:
The study included 60 eyes that had undergone PPV. Macular optical coherence tomography (OCT) findings were classified into 5 groups preoperatively and 10 groups postoperatively. Best-corrected visual acuity (BCVA) were analyzed according to pre- and postoperative OCT.
Results:
From the preoperative OCT, normal fovea with/without traction, normal fovea with preretinal hemorrhage, and tractional retinal detachment involving fovea showed an increase in BCVA after PPV (all p < 0.05). Normal fovea, epiretinal membrane and macular thickening were common after surgery. Normal fovea, epiretinal membrane and edema outside of the fovea showed good visual prognosis (BCVA >20/50). Subfoveal fibrosis, macular hole, loss of foveal depression, and serous foveal detachment showed poor visual prognosis (BCVA <20/100).
Conclusion:
Macular structural changes were various after PPV, and visual prognosis correlated with these changes.

