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Related Concept Videos

Three-Dimensional Analysis of Strain01:29

Three-Dimensional Analysis of Strain

653
Three-dimensional strain analysis is crucial for understanding how materials deform under stress, particularly in elastic, homogeneous materials. This method employs principal stress axes to simplify complex stress states into more understandable forms. Subjected to stress, a small cubic element within a material either expands or contracts along these axes, transforming into a rectangular parallelepiped. This transformation effectively illustrates the material's deformation. The principal...
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Measurements of Strain01:27

Measurements of Strain

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Strain quantifies the deformation of a material under force, typically measured as normal strain, which represents the change in length when compared with the original length. Electrical strain gauges are used for enhanced accuracy. These devices consist of a conductive wire mounted on a paper backing that adheres to the material's surface. These gauges operate on the piezoresistive effect, where the wire's electrical resistance changes in response to mechanical deformation. The strain...
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True Stress and True Strain01:28

True Stress and True Strain

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Engineering stress is calculated as the load divided by the original, undeformed cross-sectional area. It approximates a material under load. This approximation is especially relevant post-yield in ductile materials. Though engineering stress-strain diagrams are often used for their convenience and accessibility, they can sometimes fall short in accuracy, particularly when dealing with large strain values.
In contrast, true stress offers a more precise portrayal. It is computed by dividing the...
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Normal Strain under Axial Loading01:20

Normal Strain under Axial Loading

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Normal strain under axial loading is an important concept in the field of mechanics of materials. Axial loading implies the application of a force along the axis of a material, like a column or bar. This force can either compress or stretch the material. In the context of axial loading, normal strain is the deformation experienced by the material in the direction of the loading force. It's calculated as the change in length divided by the original length of the material. This unitless ratio...
1.3K
Elastic Strain Energy for Normal Stresses01:22

Elastic Strain Energy for Normal Stresses

645
Strain energy quantifies the energy stored within a material due to deformation under loading conditions, a fundamental concept in materials science and engineering. The strain energy can be modeled when a material is subjected to axial loading with uniformly distributed stress. In this scenario, the stress experienced by the material is the internal force divided by the cross-sectional area, and the strain induced is directly proportional to this stress through the modulus of elasticity.
If...
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Relation between Poisson's ratio, Modulus of Elasticity and Modulus of Rigidity01:15

Relation between Poisson's ratio, Modulus of Elasticity and Modulus of Rigidity

647
Deformation occurs in axial and transverse directions when an axial load is applied to a slender bar. This deformation impacts the cubic element within the bar, transforming it into either a rectangular parallelepiped or a rhombus, contingent on its orientation. This transformation process induces shearing strain. Axial loading elicits both shearing and normal strains. Applying an axial load instigates equal normal and shearing stresses on elements oriented at a 45° angle to the load axis.
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Related Experiment Video

Updated: Feb 26, 2026

Measurement of Pulse Propagation Velocity, Distensibility and Strain in an Abdominal Aortic Aneurysm Mouse Model
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Detecting Regional Stiffness Changes in Aortic Aneurysmal Geometries Using Pressure-Normalized Strain.

Doran S Mix1, Ling Yang2, Camille C Johnson3

  • 1Division of Vascular Surgery, Department of Surgery, University of Rochester Medical Center, Rochester, New York, USA; Department of Biomedical Engineering, Rochester Institute of Technology, Rochester, New York, USA.

Ultrasound in Medicine & Biology
|July 22, 2017
PubMed
Summary

Ultrasound elasticity imaging can assess abdominal aortic aneurysm rupture risk by measuring pressure-normalized strain in vessel walls. This technique shows potential for identifying stiffness variations and guiding clinical studies.

Keywords:
3-D printingAneurysmElasticity imagingElastographyRegistrationStrainTissue-mimicking phantomsUltrasound

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Last Updated: Feb 26, 2026

Measurement of Pulse Propagation Velocity, Distensibility and Strain in an Abdominal Aortic Aneurysm Mouse Model
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Manufacturing Abdominal Aorta Hydrogel Tissue-Mimicking Phantoms for Ultrasound Elastography Validation
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Area of Science:

  • Biomedical Engineering
  • Medical Imaging
  • Cardiovascular Research

Background:

  • Abdominal aortic aneurysms (AAAs) pose a rupture risk, necessitating improved assessment methods.
  • Current methods for evaluating AAA rupture risk lack sufficient information on mechanical properties.
  • Understanding vessel wall mechanics is crucial for predicting AAA progression and rupture.

Purpose of the Study:

  • To implement and validate a transabdominal ultrasound elasticity imaging technique.
  • To visualize and quantify pressure-normalized strain in abdominal aortic aneurysm walls.
  • To assess the potential of pressure-normalized strain as a clinical metric for AAA rupture risk.

Main Methods:

  • Developed a non-rigid image registration algorithm for ultrasound elasticity imaging.
  • Adapted the algorithm to measure total strain over a cardiac cycle.
  • Validated the method using simulated ultrasound images and physical phantoms.
  • Applied the imaging algorithm to patient data of abdominal aortic aneurysms.

Main Results:

  • The imaging algorithm successfully visualized pressure-normalized strain in vascular tissues.
  • Validated performance with simulated data and heterogeneous vessel phantoms.
  • Demonstrated clinical feasibility and potential of pressure-normalized strain as a metric.
  • Identified spatial variations in vessel tissue stiffness using pressure-normalized strain.

Conclusions:

  • Transabdominal ultrasound elasticity imaging with pressure-normalized strain shows promise for AAA assessment.
  • The technique can identify regional differences in AAA wall stiffness.
  • Further clinical studies are warranted to evaluate pressure-normalized strain in patients with aneurysmal disease.