Related Experiment Video

Updated: Feb 26, 2026

Measurement of Vibration Detection Threshold and Tactile Spatial Acuity in Human Subjects
07:32

Measurement of Vibration Detection Threshold and Tactile Spatial Acuity in Human Subjects

Published on: September 1, 2016

13.2K

Piezo2 in Cutaneous and Proprioceptive Mechanotransduction in Vertebrates

E O Anderson1, E R Schneider1, S N Bagriantsev1

  • 1Yale University, New Haven, CT, United States.

Current Topics in Membranes
|July 22, 2017
PubMed

Keywords:
Dorsal root gangliaMechanoreceptionMechanosensitivityMechanotransductionPiezo2ProprioceptionSomatosensitivityTrigeminal ganglia

More Related Videos

Ex Vivo Analysis of Mechanically Activated Ca2+ Transients in Urothelial Cells05:35

Ex Vivo Analysis of Mechanically Activated Ca2+ Transients in Urothelial Cells

Published on: September 28, 2022

1.4K
One-channel Cell-attached Patch-clamp Recording13:07

One-channel Cell-attached Patch-clamp Recording

Published on: June 9, 2014

25.5K

Related Concept Videos

Mechanically-gated Ion Channels01:12

Mechanically-gated Ion Channels

Mechanically-gated ion channels are proteins found in eukaryotic and prokaryotic cell membranes that open in response to mechanical stress. Tension, compression, swelling, and shear stress can alter the conformation of the protein, opening a transmembrane channel that allows the passage of ions for signal transmission. In eukaryotes, mechanically-gated channels are distributed in several regions like the neurons, lungs, skin, bladder, and heart, where they play critical roles in numerous...
7.9K
Sensory Functions of the Skin01:16

Sensory Functions of the Skin

The skin is the largest organ of the human body and plays a crucial role in our sensory perception. It contains a vast network of sensory receptors that contribute to the skin's protective function by perceiving physical, biological, and environmental cues and generating relevant responses.
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
8.8K
Tension Response at Adherens Junctions01:26

Tension Response at Adherens Junctions

The adherens junctions that anchor cells together are multi-protein complexes that dynamically adapt to mechanical stimuli such as tensile forces and shear stress. Mechanosensory proteins in these junctions can sense such mechanical stimuli and undergo a shift in their conformation, resulting in an altered function — a process called mechanotransduction.
α-Catenin as a Mechanosensory Protein
The α-catenin of adherens junctions is an allosteric protein with three VH (vinculin...
3.7K
Somatosensation01:33

Somatosensation

The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
43.9K
Overview of Somatic Sensory Pathways01:29

Overview of Somatic Sensory Pathways

Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
9.0K
Tactile and Chemical Senses01:27

Tactile and Chemical Senses

Tactile senses encompass touch, temperature, and pain, each mediated by specific receptors. Touch receptors detect mechanical energy or pressure against the skin. Sensory fibers from these receptors enter the spinal cord and relay information to the brain stem. Here, most fibers cross over to the opposite side of the brain. The touch information then moves to the thalamus, which projects a map of the body's surface onto the somatosensory areas of the parietal lobes in the cerebral cortex.
1.1K