Eve's garden: myths, legends and secrets unmasked

Area of Science:

• Microbiology
• Women's Health
• Microbiome Research

Background:

• The vaginal microbiome is a complex interacting microbial community in women.
• Defining a 'healthy' vaginal microbiome remains challenging despite advanced research methods.
• Interest in vaginal microbiome dysbiosis is growing, extending beyond bacterial vaginosis.

Discussion:

• This special issue explores inter- and intra-microorganism interactions within the vaginal microbiome.
• It examines the virulence factors deployed by specific microorganisms in this community.
• Current knowledge on the dynamics of the vaginal microbial ecosystem is summarized.

Key Insights:

• The vaginal microbiome's composition and function are dynamic and not universally defined.
• Dysbiosis, or imbalance, in the vaginal microbiome has implications beyond known conditions like bacterial vaginosis.
• Understanding microbial interactions and virulence is crucial for comprehending vaginal health.

Outlook:

• Further research is needed to establish clear definitions of vaginal microbiome health.
• Investigating the role of microbial interactions and virulence factors will advance understanding of gynecological health.
• This special issue provides a foundation for future studies on the vaginal microbiome.