Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genomics02:02

Genomics

41.1K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
41.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diversity, Equity, and Inclusion in Multiple Myeloma: A Call to Action.

Journal of the advanced practitioner in oncology·2025
Same author

Multiple Myeloma: Validation of the Values and Preferences Elicitation Questionnaire- Cure and Survival Preference Scale (VPEQ-CSPS).

Clinical lymphoma, myeloma & leukemia·2024
Same author

Cultural Competence of Student Registered Nurse Anesthetists in Illinois.

AANA journal·2021
Same author

Stress and Coping: A Literature Review of Everyday Stressors and Strategies to Cope in Pediatric Patients With Cancer.

Clinical journal of oncology nursing·2021
Same author

Examining effective communication in nursing practice during COVID-19: A large-scale qualitative study.

International nursing review·2021
Same author

How to Prevent Endotracheal Tube Cuff Overinflation: "5 for 25".

AANA journal·2021

Related Experiment Video

Updated: Feb 26, 2026

Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube SWCNT-delivered MALAT1 Antisense Oligos
07:24

Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube SWCNT-delivered MALAT1 Antisense Oligos

Published on: December 13, 2018

6.9K

Multiple Myeloma Genomics: A Systematic Review.

Casey J Weaver, Joseph D Tariman

    Seminars in Oncology Nursing
    |July 22, 2017
    PubMed
    Summary
    This summary is machine-generated.

    Genomic variants like KRAS and TP53 are linked to poor outcomes in multiple myeloma (MM). Understanding these genetic changes is crucial for targeted therapies and patient care in MM.

    Keywords:
    genomicsmultiple myelomanext-generation sequencingtranslation research

    More Related Videos

    Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis
    10:04

    Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis

    Published on: May 1, 2015

    13.5K
    Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice
    05:32

    Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

    Published on: January 7, 2019

    7.3K

    Related Experiment Videos

    Last Updated: Feb 26, 2026

    Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube SWCNT-delivered MALAT1 Antisense Oligos
    07:24

    Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube SWCNT-delivered MALAT1 Antisense Oligos

    Published on: December 13, 2018

    6.9K
    Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis
    10:04

    Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis

    Published on: May 1, 2015

    13.5K
    Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice
    05:32

    Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

    Published on: January 7, 2019

    7.3K

    Area of Science:

    • Genomic medicine
    • Oncology
    • Hematology

    Background:

    • Multiple myeloma (MM) is a hematologic malignancy characterized by genetic complexity.
    • Identifying prognostic genomic alterations is critical for personalized treatment strategies.

    Purpose of the Study:

    • To review genomic variants associated with poor prognosis in multiple myeloma (MM).
    • To identify genetic and genomic changes in MM using next-generation sequencing (NGS).

    Main Methods:

    • An integrative review of 33 peer-reviewed articles was conducted.
    • Literature search performed using PubMed, EBSCOhost, and DePaul WorldCat Libraries Worldwide.
    • Next-generation sequencing, including whole-genome and exome sequencing, was utilized to identify genetic changes.

    Main Results:

    • Commonly reported genetic alterations include KRAS, NRAS, TP53, FAM46C, BRAF, DIS3, ATM, and CCND1.
    • These genetic changes are implicated in MM pathogenesis and serve as potential therapeutic targets.

    Conclusions:

    • Rapid advancements in MM genetics and genomics necessitate updated clinical understanding.
    • Oncology nurses require genomic competencies to support patients navigating complex genetic alterations and referrals.