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Insight into immunocytes infiltrations in polymorphous light eruption

Dongyun Lei1, Wenjuan Wu1, Li Yang1

  • 1Department of Dermatology, First Affiliated Hospital of Kunming Medical University, Institute of Dermatology & Venereology of Yunnan Province, Kunming, Yunnan, China.

Biotechnology Advances
|July 22, 2017
PubMed

Polymorphous light eruption (PLE) which is one of the most common photodermatoses has been demonstrated to be immune-mediated disorder. Resistance to UV-induced immunosuppression resulting from differential immune cells infiltration and cytokines secretion has been highlighted in the pathogenesis of PLE. In this study, we reviewed differential patterns of immune cells infiltrations and cytokines secretion that may contribute to PLE occurrence and development.

Keywords:
CytokinesImmune cellsImmunosuppressionPhotodermatosesPolymorphous light eruption

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