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Characteristics of CSF Velocity-Time Profile in Posttraumatic Syringomyelia.
1From Neuroscience Research Australia (J.Y., B.B.L., L.B.), Randwick, New South Wales, Australia.
AJNR. American Journal of Neuroradiology
|July 22, 2017
Summary
Patients with posttraumatic syringomyelia exhibit altered cerebrospinal fluid (CSF) flow timing, with shorter caudal flow duration, compared to healthy individuals. This suggests temporal CSF flow changes may contribute to syrinx development.
Area of Science:
- Neurology
- Neurosurgery
- Medical Imaging
Background:
- Syringomyelia development is linked to altered cerebrospinal fluid (CSF) dynamics.
- Previous research has not clearly defined CSF flow velocity differences in posttraumatic syringomyelia.
Purpose of the Study:
- To quantify and compare CSF flow velocity above and below a syrinx in posttraumatic syringomyelia patients.
- To establish differences in CSF flow dynamics between patients and healthy controls.
Main Methods:
- Phase-contrast MRI was employed to measure CSF flow velocity.
- Measurements were taken at the skull base and around the syrinx.
- CSF velocity profiles were compared between posttraumatic syringomyelia patients and controls.
Main Results:
- CSF flow velocity was uniform along the spinal canal in syringomyelia patients.
- Peak CSF velocities were significantly lower in patients compared to controls.
- The duration of caudal CSF flow was significantly shorter in patients.
Conclusions:
- CSF flow in posttraumatic syringomyelia is temporally distinct from healthy controls.
- Findings support the hypothesis that altered spinal CSF flow timing contributes to syrinx formation.
