Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Glutamate-induced vocalization in the squirrel monkey.

U Jürgens, K Richter

    Brain Research
    |May 14, 1986
    PubMed
    Summary

    Researchers identified specific brain regions in squirrel monkeys that control vocalization. Glutamate injections pinpointed relay stations in the substantia innominata and brainstem reticular formation crucial for vocal communication.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Data assimilation in the decision support system rodos.

    Radiation protection dosimetry·2003
    Same author

    Increasing sample throughput in pharmacological studies by using dual-column liquid chromatography with tandem mass spectrometry.

    Journal of chromatography. A·2003
    Same author

    Neurotropic effect of juvenile hormone III in larvae of the cockroach, Periplaneta americana.

    Journal of insect physiology·2003
    Same author

    Reproducibility of forced inspiratory and expiratory volumes after bronchodilation in patients with COPD or asthma.

    Respiratory medicine·2003
    Same author

    The effect of storage on allergen and microbial agent levels in frozen house dust.

    Allergy·2003
    Same author

    Dose reduction of inhaled corticosteroids under concomitant medication with montelukast in patients with asthma.

    The European respiratory journal·2002

    Area of Science:

    • Neuroscience
    • Animal Behavior
    • Primate Research

    Background:

    • Electrical stimulation can elicit vocalizations from various brain sites in squirrel monkeys.
    • Understanding the neural pathways controlling vocalization is key to deciphering complex communication.
    • Mono-sodium-L-glutamate is a neurochemical tool used to probe neuronal function.

    Purpose of the Study:

    • To map brain regions involved in vocalization control using glutamate stimulation.
    • To compare glutamate stimulation results with previous electrical stimulation findings.
    • To identify relay stations and motor coordination centers for vocalization.

    Main Methods:

    • 164 brain sites previously identified via electrical stimulation were tested with mono-sodium-L-glutamate injections.
    • Vocalizations produced were analyzed for acoustic structure.
    • Positive sites were mapped to identify specific brain nuclei and pathways.

    Main Results:

    • 31 out of 164 tested sites yielded vocalizations upon glutamate injection.
    • Positive sites included substantia innominata, periventricular/periaqueductal gray, and pontine/medullary reticular formation.
    • Forebrain and midbrain vocalizations had normal acoustic structure; pontine and medullary vocalizations were often artificial.

    Conclusions:

    • Substantia innominata, periaqueductal gray, and pontine/medullary reticular formation are critical relay stations for vocalization.
    • The periaqueductal gray is the lowest relay station above motor coordination centers.
    • Motor coordination neurons for vocalization are located in the brainstem reticular formation and specific cranial nerve nuclei.

    Related Experiment Videos