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Updated: Feb 26, 2026

Brain Imaging Investigation of the Neural Correlates of Emotional Autobiographical Recollection
Published on: August 26, 2011
Picture free recall performance linked to the brain's structural connectome
David Coynel1,2, Leo Gschwind1,2,3, Matthias Fastenrath1,2
1Division of Cognitive Neuroscience Department of Psychology University of Basel Basel Switzerland.
Introduction:
Memory functions are highly variable between healthy humans. The neural correlates of this variability remain largely unknown.
Methods:
Here, we investigated how differences in free recall performance are associated with DTI-based properties of the brain's structural connectome and with grey matter volumes in 664 healthy young individuals tested in the same MR scanner.
Results:
Global structural connectivity, but not overall or regional grey matter volumes, positively correlated with recall performance. Moreover, a set of 22 inter-regional connections, including some with no previously reported relation to human memory, such as the connection between the temporal pole and the nucleus accumbens, explained 7.8% of phenotypic variance.
Conclusions:
In conclusion, this large-scale study indicates that individual memory performance is associated with the level of structural brain connectivity.
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