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Updated: Feb 26, 2026

Murine Corneal Transplantation: A Model to Study the Most Common Form of Solid Organ Transplantation
Published on: November 17, 2014
Corneal blindness and current major treatment concern-graft scarcity
Kah Hie Wong1, Ka Wai Kam2, Li Jia Chen1,2
1Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong Kong, China.
Abstract:
According to World Health Organization, the global prevalence of blindness in 2010 was 39 million people, among which 4% were due to corneal opacities. Often, the sole resort for visual restoration of patients with damaged corneas is corneal transplantation. However, despite rapid developments of surgical techniques, instrumentations and immunosuppressive agents, corneal blindness remains a prevalent global health issue. This is largely due to the scarcity of good quality corneal grafts. In this review, the causes of corneal blindness, its major treatment options, and the major contributory factors of corneal graft scarcity with potential solutions are discussed.
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