Related Experiment Video
Updated: Feb 26, 2026

Author Spotlight: Integrating Tai Chi with Mindfulness Training to Achieve an Effective Mind-Body Exercise
Published on: July 14, 2023
Anemia: an independent risk factor of diabetic peripheral neuropathy in type 2 diabetic patients
Fan Wu1, Yuanyuan Jing1, Xiaojun Tang2
1Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Youyi Road No. 1, Yuzhong District, Chongqing, 400016, China.
Aims:
Recently, the association between anemia and diabetic microvascular complications has been studied. Diabetic peripheral neuropathy (DPN) is also a common complication of type 2 diabetes mellitus (T2DM), while the relationship between anemia and DPN is rarely investigated. The aim of this study is to evaluate the association between anemia and DPN in T2DM.
Methods:
In this cross-sectional study, 1134 T2DM inpatients were enrolled. The diagnosis of DPN was based on neuropathy system score (NSS) and neuropathy disability score (NDS). Logistic regression was conducted to analyze the association between anemia and DPN.
Results:
The proportions of anemia in DPN and non-DPN group were 25.4 and 15.2%, respectively. Compared with non-anemia group, the proportions of moderate/severe NSS (42.7 vs. 24.5%, P < 0.001) and moderate/severe NDS (51.5 vs. 38.0%, P < 0.001) were higher while the nerve conduction velocity (NCV) was lower in anemia group. Univariate logistic regression analysis showed patients with anemia possessed an increased risk of DPN [OR = 1.906, 95%CI: 1.416, 2.567, P < 0.001]. Multivariate logistic regression analysis suggested anemia was an independent risk factor of DPN in model 1 and model 2 [model 1: OR = 1.472, 95%CI: 1.047, 2.070, P = 0.026; model 2: OR = 1.448, 95%CI: 1.013, 2.071, P = 0.043].
Conclusions:
Anemia is an independent risk factor of DPN in T2DM patients.
Related Concept Videos
Diabetes Mellitus: Type 2 and Gestational
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Psychoneuroimmunology: Diabetes and Cancer
Diabetes: Symptoms, Diagnosis, and Complications
Peripheral Artery Disease IV: Nursing Management
Carbohydrate Metabolism
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...

