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Updated: Feb 26, 2026
Application of Laparoscopic Hepatectomy Combined with Intraoperative Microwave Ablation in Colorectal Cancer Liver Metastasis
Published on: March 3, 2023
A comparative study of laparoscopic microwave ablation with laparoscopic radiofrequency ablation for colorectal liver
1The Affiliated Hospital of Southwest Medical University, Luzhou 646000, People's Republic of China.
Purpose:
Laparoscopic thermal ablation is a common alternative to surgical resection for treating colorectal liver metastasis, particularly for metastases located in difficult-to-reach regions. This study aimed to compare the short- and longterm outcomes of laparoscopic radiofrequency ablation (LRFA) and laparoscopic microwave ablation (LMWA) used for treating colorectal liver metastasis.
Methods:
Data from patients with colorectal liver metastasis who had undergone LRFA or LMWA from January 2010 to January 2016 were examined. Baseline data, postoperative 30-day complications, complete ablation rates, local tumor progression rates, and disease-free (DFS) and overall survival (OS) rates were compared between the two treatment groups.
Results:
A total of 179 patients with colorectal liver metastasis (71 with LMWA and 108 with LRFA) were treated via the laparoscopic approach. Major postoperative 30-day complication rates were 11.1% and 12.7% in the LRFA and LMWA groups, respectively (p=0.046). No perioperative or postoperative 30-day deaths occurred. Local tumor progression (LTP) rates were 10.2% (11/108) and 1.4% (1/71) in the LRFA and LMWA groups (p=0.046), respectively. Fiveyear OS rates were 56% and 58% (p=0.498) and 5-year DFS rates were 41% and 39% (p=0.557) in the LRFA and LMWA groups, respectively.
Conclusions:
LRFA and LMWA appear to be safe for treating colorectal liver metastasis. The OS and DFS rates were similar, although LTP rates were lower in the LMWA group than in the LRFA group.
