Related Experiment Video
Updated: Feb 26, 2026

Author Spotlight: Investigating the Tolerance of Cabbage Butterflies to Urban Pollutants
Published on: August 18, 2023
Toxicology of Lead and Its Damage to Mammalian Organs
Abstract:
The toxicity of lead has been appreciated for centuries. Lead is a commonly used metal in industrialized nations, which results in the release of lead into the environment. Governmental agencies regulate the amount of lead permissible for workers to be exposed to; however, unregulated environmental lead exposure is a high concern. While essential metals have physiologic roles, there are no health benefits from lead intake. In this chapter, we discuss sources of lead exposure, the absorption, distribution, and elimination of lead from the human body, and molecular mechanisms of lead-induced toxicity. We also discuss the evidence on the association between lead exposure and blood pressure, and the influence of sociodemographic, lifestyle and environmental determinants of lead exposure in the general population. We highlight the effects on the nervous system, kidney, immune system, blood, reproductive system, and bones.
More Related Videos
09:23Removal of Trace Elements by Cupric Oxide Nanoparticles from Uranium In Situ Recovery Bleed Water and Its Effect on Cell Viability
Published on: June 21, 2015
06:00Experimental Protocol for Using Drosophila As an Invertebrate Model System for Toxicity Testing in the Laboratory
Published on: July 10, 2018
Related Concept Videos
Toxicity Testing in Animals
The Periodic Table and Organismal Elements
Periodic Table Provides Information...
The Periodic Table and Organismal Elements
Toxic Reactions: Overview
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Types of Toxins
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Drug Toxicity: Dose-Dependent Reactions