Flow cytometry based monocyte subset analysis accurately distinguishes chronic myelomonocytic leukemia from myeloproliferative neoplasms with associated monocytosis

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Characterization of Human Monocyte Subsets by Whole Blood Flow Cytometry Analysis
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Characterization of Human Monocyte Subsets by Whole Blood Flow Cytometry Analysis

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M M Patnaik1, M M Timm2, R Vallapureddy1

  • 1Division of Hematology, Department of Internal Medicine, Mayo Clinic, MN, USA.

Blood Cancer Journal
|July 22, 2017
PubMed
Abstract

No abstract available in PubMed .

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The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
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