Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

1.8K
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
1.8K
Tissue Transplantation01:24

Tissue Transplantation

1.1K
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
1.1K
Regulation of Hematopoietic Stem Cells01:01

Regulation of Hematopoietic Stem Cells

4.2K
All blood and immune cells are produced from the multipotent hematopoietic stem cells (HSCs) by the process of hematopoiesis. However, they all have a limited life span. In addition, many are depleted in immune surveillance or combatting an injury or infection. This makes blood one of the most regenerative tissues. Hematopoiesis helps replenish these blood and immune cells, restoring the body's normal functioning. However, overproduction of blood and immune cells can make them cancerous or...
4.2K
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

566
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
566
Hematopoiesis01:21

Hematopoiesis

9.3K
The process of blood cell formation is called hematopoiesis. Hematopoiesis starts early during development, on the seventh day of embryogenesis. This phase of hematopoiesis is called the primitive wave, wherein the extraembryonic yolk sac allows the production of erythroid cells and endothelial cells from a common precursor called hemangioblast. The erythroid cells provide oxygen to support the growth of the rapidly dividing embryo. Hemangioblasts later develop into hematopoietic stem cells or...
9.3K
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

4.7K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Probiotics: multifunctional microorganisms for human health and biotechnological applications.

Frontiers in microbiology·2026
Same author

AI in multi-omics analysis of type 2 diabetes.

Progress in molecular biology and translational science·2026
Same author

Seventh Ã…land Island Meeting on von Willebrand Disease.

Haemophilia : the official journal of the World Federation of Hemophilia·2026
Same author

Exploring the oral microbiome: from traditional techniques to advanced omics and databases.

Antonie van Leeuwenhoek·2026
Same author

A Second Factor VIIIa Mimetic for Hemophilia A.

The New England journal of medicine·2026
Same author

Response to hemophilia B gene therapy based on adenoassociated virus serotype 5 antibody status.

Research and practice in thrombosis and haemostasis·2026

Related Experiment Video

Updated: Feb 26, 2026

Competitive Transplants to Evaluate Hematopoietic Stem Cell Fitness
08:53

Competitive Transplants to Evaluate Hematopoietic Stem Cell Fitness

Published on: August 31, 2016

16.0K

Cost and quality issues in establishing hematopoietic cell transplant program in developing countries.

Shahrukh K Hashmi1, Alok Srivastava2, Walid Rasheed3

  • 1Oncology Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia; Department of Internal Medicine, Mayo Clinic, MN, USA.

Hematology/Oncology and Stem Cell Therapy
|July 22, 2017
PubMed
Summary

Establishing new hematopoietic cell transplant (HCT) programs in developing nations faces challenges like resource scarcity and cost. Prioritizing quality and value is crucial for leadership when launching HCT services.

Keywords:
CostHematopoietic cell transplantationQualityTransplant

More Related Videos

Author Spotlight: Exploring the Lifespan Dynamics of Healthy Human Hematopoiesis
03:40

Author Spotlight: Exploring the Lifespan Dynamics of Healthy Human Hematopoiesis

Published on: December 8, 2023

1.9K
Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies
11:59

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies

Published on: September 6, 2017

7.9K

Related Experiment Videos

Last Updated: Feb 26, 2026

Competitive Transplants to Evaluate Hematopoietic Stem Cell Fitness
08:53

Competitive Transplants to Evaluate Hematopoietic Stem Cell Fitness

Published on: August 31, 2016

16.0K
Author Spotlight: Exploring the Lifespan Dynamics of Healthy Human Hematopoiesis
03:40

Author Spotlight: Exploring the Lifespan Dynamics of Healthy Human Hematopoiesis

Published on: December 8, 2023

1.9K
Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies
11:59

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies

Published on: September 6, 2017

7.9K

Area of Science:

  • Hematology
  • Transplant Medicine
  • Healthcare Management

Background:

  • Hematopoietic cell transplant (HCT) activity has seen substantial global growth over the last 20 years.
  • Developing countries face unique challenges in establishing HCT programs, including limited resources, expertise shortages, and high initial costs.
  • Balancing cost-effectiveness with high-quality care is a key consideration for new HCT program leadership.

Purpose of the Study:

  • To analyze the primary cost and quality challenges encountered when initiating new HCT programs, particularly in resource-limited settings.
  • To provide real-world examples of HCT program establishment in developing countries despite financial constraints.
  • To offer guidance for leadership on balancing quality and cost in new HCT program development.

Main Methods:

  • Review of challenges in establishing HCT programs from cost and quality perspectives.
  • Case studies of two developing countries successfully launching HCT programs under financial constraints.
  • Incorporation of recommendations from the Worldwide Network of Blood and Marrow Transplantation (WBMT) for HCT program requirements.

Main Results:

  • Key challenges include a lack of trained personnel, significant start-up expenses for tertiary care facilities, and maintaining quality standards.
  • Successful HCT program initiation is possible even with substantial financial limitations, as demonstrated by case studies.
  • WBMT provides essential recommendations for the foundational requirements of new HCT programs.

Conclusions:

  • Leadership must prioritize both quality and cost-efficiency when developing new HCT programs in any setting.
  • Addressing personnel shortages and managing start-up costs are critical hurdles for HCT program establishment in developing countries.
  • This review serves as a guide for balancing high-quality patient care with financial sustainability in nascent HCT programs.