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Multiple cholesterol emboli syndrome simulating systemic necrotizing vasculitis.

D K Young, M F Burton, J H Herman

The Journal of Rheumatology

|April 1, 1986

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Multiple cholesterol emboli syndrome, often seen with severe atherosclerosis, can mimic vasculitis. Early diagnosis via tissue biopsy is crucial to avoid incorrect treatments like steroids.

Area of Science:

Cardiology
Pathology
Nephrology

Background:

Severe atherosclerotic vascular disease can lead to multiple cholesterol emboli.
Cholesterol emboli syndrome (CES) presents a diagnostic challenge due to its mimicry of other conditions.

Observation:

CES can present with widespread visceral infarctions.
Laboratory findings may include leukocytosis, eosinophilia, thrombocytopenia, hypocomplementemia, and elevated sedimentation rate.
CES often occurs post-intraarterial procedures like cardiac catheterization.

Findings:

Clinical presentation of CES can simulate systemic necrotizing vasculitis.
Diagnosis is confirmed through biopsy of affected tissue.

Implications:

Related Experiment Videos

Accurate diagnosis of CES is vital.
Avoiding inappropriate steroid and cytotoxic therapies prevents adverse outcomes.