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Linking clinical quality indicators to research evidence - a case study in asthma management for children
Miew Keen Choong1, Guy Tsafnat1, Peter Hibbert2
1Centre for Health Informatics, Australian Institute of Health Innovation, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.
Insights
Most clinical quality indicators for pediatric asthma management are supported by research evidence from randomized controlled trials (RCTs). This study links 95% of indicators to RCT outcomes, supporting evidence-based healthcare quality assessment.
Area of Science:
- Pediatric Pulmonology
- Health Services Research
- Evidence-Based Medicine
Background:
- Clinical quality indicators (CQIs) are crucial for monitoring healthcare performance.
- A knowledge gap exists regarding the research evidence base for commonly used CQIs.
- This study addresses the extent to which pediatric asthma CQIs align with research findings.
Purpose of the Study:
- To quantify the link between pediatric asthma management CQIs and outcomes reported in randomized controlled trials (RCTs).
- To inform methods for improving the efficiency and accuracy of CQI development.
- To ensure that asthma care quality metrics are grounded in scientific evidence.
Main Methods:
- Extracted national-level pediatric asthma indicators from databases like the National Quality Measures Clearinghouse.
- Collected outcome measures from English-language RCT reports on pediatric asthma (2005-2014).
- Mapped indicators and RCT outcomes to Unified Medical Language System (UMLS) concepts for linkage.
Main Results:
- Identified 39 pediatric asthma management indicators and 562 relevant RCTs.
- Established a link between approximately 95% (37/39) of the indicators and RCT outcome measures.
- Demonstrated a strong connection between clinical quality indicators and research evidence in this field.
Conclusions:
- A significant majority of pediatric asthma quality indicators can be traced back to relevant RCT evidence.
- The developed methodology offers a scalable approach for assessing new indicators against research.
- This supports the use of evidence-based practices in pediatric asthma quality assessment and improvement.
Background:
Clinical quality indicators are used to monitor the performance of healthcare services and should wherever possible be based on research evidence. Little is known however about the extent to which indicators in common use are based on research. The objective of this study is to measure the extent to which clinical quality indicators used in asthma management in children with outcome measurements can be linked to results in randomised controlled clinical trial (RCT) reports. This work is part of a broader research program to trial methods that improve the efficiency and accuracy of indicator development.
Methods:
National-level indicators for asthma management in children were extracted from the National Quality Measures Clearinghouse database and the National Institute for Health and Care Excellence quality standards by two independent appraisers. Outcome measures were extracted from all published English language RCT reports for asthma management in children below the age of 12 published between 2005 and 2014. The two sets were then linked by manually mapping both to a common set of Unified Medical Language System (UMLS) concepts.
Results:
The analysis identified 39 indicators and 562 full text RCTs dealing with asthma management in children. About 95% (37/39) of the indicators could be linked to RCT outcome measures.
Conclusions:
It is possible to identify relevant RCT reports for the majority of indicators used to assess the quality of asthma management in childhood. The methods reported here could be automated to more generally support assessment of candidate indicators against the research evidence.
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