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The most important allergens in allergic rhinitis.

E Holopainen, O P Salo, E Tarkiainen

    Acta Oto-Laryngologica. Supplementum
    |January 1, 1979
    PubMed
    Summary

    This study identifies key allergens in 770 patients with nasal symptoms. Grass, birch, and mugwort pollens were most significant, while house dust sensitivity was common, though mite sensitivity was lower.

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    Area of Science:

    • Allergy and Immunology
    • Environmental Health

    Background:

    • Allergic rhinitis affects a significant patient population with diverse triggers.
    • Identifying prevalent allergens is crucial for effective diagnosis and management.

    Purpose of the Study:

    • To report the distribution of various allergens in patients presenting with seasonal and perennial nasal symptoms.
    • To determine the clinical significance of identified allergens.

    Main Methods:

    • Allergy work-up was performed on 770 patients.
    • Patients presented with seasonal and perennial nasal symptoms.
    • Allergen distribution and reaction percentages were analyzed.

    Main Results:

    • Positive reactions to grass, tree, and herb pollens were high (30-40%).
    • Clinically significant pollens included grasses (Timothy, Alopecurus, Kentucky Blue, Meadow fescue), birch, and mugwort (Artemisia).
    • House dust sensitivity was found in 44% of patients, while mite extract sensitivity was 10%; animal danders (13-18%) and moulds (9%) were less common.

    Conclusions:

    • Grasses, birch, and mugwort are important pollen allergens in patients with nasal symptoms.
    • House dust is a common allergen in perennial rhinitis in Nordic countries, but specific mite sensitivity is less prevalent.
    • Further research is needed to elucidate specific house dust components responsible for allergic reactions.

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