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Published on: December 4, 2015
Malaria in Children
Lauren M Cohee1, Miriam K Laufer1
1Division of Malaria Research, Institute for Global Health, University of Maryland School of Medicine, HSF-II, Room 480, 685 West Baltimore Street, Baltimore, MD 21201, USA.
Insights
Malaria remains a significant global health threat, causing substantial mortality and posing risks to travelers. Prompt diagnosis and treatment are crucial for managing this disease effectively.
Area of Science:
- Tropical medicine
- Infectious diseases
- Public health
Background:
- Malaria is a major cause of illness and death in endemic regions, with significant global health implications.
- Travelers to malaria-endemic areas are at risk and require careful evaluation if they develop fever upon return.
- Timely diagnosis and effective treatment are vital to prevent severe complications and save lives.
Purpose of the Study:
- To emphasize the critical importance of considering malaria in the differential diagnosis of febrile travelers.
- To highlight the necessity of prompt and effective treatment for malaria patients.
- To underscore the significance of understanding Plasmodium species, epidemiology, and drug resistance for optimal treatment selection.
Main Methods:
- Literature review on malaria epidemiology and treatment guidelines.
- Analysis of clinical case presentations and diagnostic considerations.
- Synthesis of information on Plasmodium species and drug resistance patterns.
Main Results:
- Malaria caused an estimated 438,000 deaths in 2015.
- Fever in returning travelers necessitates malaria evaluation.
- Effective treatment choice depends on geographic origin and Plasmodium species.
Conclusions:
- Prompt malaria diagnosis and treatment are life-saving interventions.
- Understanding geographic-specific Plasmodium characteristics is essential for effective malaria management.
- Malaria remains a critical public health concern requiring vigilance in endemic areas and among travelers.
Abstract:
Malaria is a leading cause of morbidity and mortality in endemic areas, leading to an estimated 438,000 deaths in 2015. Malaria is also an important health threat to travelers to endemic countries and should be considered in evaluation of any traveler returning from a malaria-endemic area who develops fever. Considering the diagnosis of malaria in patients with potential exposure is critical. Prompt provision of effective treatment limits the complications of malaria and can be life-saving. Understanding Plasmodium species variation, epidemiology, and drug-resistance patterns in the geographic area where infection was acquired is important for determining treatment choices.
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