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[Asthma and heroin use].

Michel Underner1, Jean Perriot2, Gérard Peiffer3

  • 1Université de Poitiers, unité de recherche clinique Pierre-Deniker, centre hospitalier Henri-Laborit, 370, avenue Jacques-Cœur, CS 10587, 86021 Poitiers cedex, France.

Presse Medicale (Paris, France : 1983)
|July 24, 2017
PubMed
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Heroin use is linked to asthma development and exacerbations, increasing the risk of severe respiratory complications and death. Healthcare providers should screen for heroin use in asthma patients and support cessation efforts.

Area of Science:

  • Pulmonology
  • Addiction Medicine
  • Toxicology

Background:

  • Heroin use is associated with various respiratory issues.
  • Asthma is a significant respiratory complication linked to heroin consumption.

Purpose of the Study:

  • To conduct a systematic literature review on asthma in heroin users.
  • To analyze the relationship between heroin use and asthma onset, exacerbations, and outcomes.

Main Methods:

  • Systematic literature search of Medline (1980-2017) using keywords related to asthma and heroin/opiates.
  • Selection of 23 studies from 97 initially identified articles based on title/abstract review.
  • Inclusion of case reports, cross-sectional, case-control, and longitudinal studies.

Main Results:

Related Experiment Videos

  • Heroin users showed a higher prevalence of asthma and bronchial hyperreactivity.
  • Heroin use was linked to asthma onset in 28-31% of cases and acute exacerbations, particularly with inhaled use.
  • Heroin users had lower treatment adherence, increased emergency department visits, and higher rates of intensive care unit admission and mechanical ventilation.

Conclusions:

  • Heroin use can trigger asthma onset and severe exacerbations, potentially requiring intubation and ventilation.
  • Identifying heroin use is crucial in young individuals presenting with asthma exacerbations.
  • Assisting heroin users in discontinuing consumption is essential for managing asthma and preventing severe outcomes.