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Published on: July 15, 2019
Viral Infection of the Heart: Pathogenesis and Diagnosis
Mateusz Kuffner1, Agnieszka Pawlak1, Maciej Przybylski2
1Department of Invasive Cardiology, Central Clinical Hospital of the Ministry of Interior, Warsaw, Poland</br> Mossakowski Medical Research Centre Polish Academy of Sciences, Warsaw, Poland.
Abstract:
Viral infections of the heart cause serious clinical problems, either as infectious myocarditis, which usually is a consequence of acute infection or as idiopathic dilated cardiomyopathy, resulting rather from a chronic infection. This minireview presents an up-to-date view on pathomechanisms of viral infection of the heart tissues, the role of immune system in controlling infectious process at its various stages and current possibilities of recognizing viral infection of the heart with use of both cardiological and virological methods. Our goal was to present the variety of known viral agents causing heart infection, level of complexity in mutual virus-cell interactions, and consequent clinical scenarios.
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