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Updated: Feb 26, 2026

Cell Population Analyses During Skin Carcinogenesis
Published on: August 21, 2013
Smokers versus Smoking: Is There Detection Bias for Keratinocyte Carcinomas?
1Department of Dermatology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
Abstract:
Dusingize et al. used a prospective observational cohort study to demonstrate a decreased risk of basal cell carcinoma and an increased risk of squamous cell carcinoma among smokers. This association disappeared after stratifying for skin screening visits, demonstrating the important role of detection bias. In the absence of randomized clinical trials, well-designed and critically analyzed observational studies can provide similarly valuable evidence.
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