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Intensive lifestyle intervention is particularly advantageous in poorly controlled type 2 diabetes
E Sbroma Tomaro1, R Pippi1, E Reginato1
1Healthy Lifestyle Institute, C.U.R.I.A.Mo. (Centro Universitario Ricerca Interdipartimentale Attività Motoria), University of Perugia, Via G. Bambagioni, 19 06126 Perugia, Italy.
Summary
An intensive lifestyle intervention significantly improved metabolic and clinical parameters in people with type 2 diabetes. This approach is particularly beneficial for individuals with inadequate glucose control, showing lasting positive effects.
Area of Science:
- Endocrinology
- Metabolic Diseases
- Public Health
Background:
- Type 2 diabetes management often requires lifestyle interventions.
- The effectiveness of lifestyle changes in individuals with inadequate glycemic control remains under investigation.
- Baseline glycosylated hemoglobin (HbA1c) levels may influence intervention outcomes.
Purpose of the Study:
- To assess the impact of baseline HbA1c on the efficacy of an intensive lifestyle intervention in type 2 diabetes patients.
- To evaluate changes in metabolic, clinical, and strength parameters following the intervention.
- To determine if baseline glycemic control influences intervention success.
Main Methods:
- A 3-month structured, multidisciplinary lifestyle intervention was implemented.
- 222 type 2 diabetes patients with varying baseline HbA1c levels participated.
- Measurements included anthropometric, biochemical, clinical, and fitness parameters at baseline, 3 months, and 2-year follow-up.
Main Results:
- Significant improvements were observed in HbA1c, BMI, waist circumference, and blood pressure at 3 months and 2 years.
- Hypoglycemic medication use decreased significantly.
- Patients with higher baseline HbA1c (≥7.71%) showed the most substantial improvements in HbA1c, blood glucose, and triglycerides.
Conclusions:
- Intensive lifestyle interventions are effective for type 2 diabetes management.
- These interventions yield significant and sustained improvements in metabolic and clinical health.
- The positive effects are particularly pronounced in individuals with poorer initial glycemic control.
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